• • DRAMP ID

  • DRAMP02843

• • Peptide Name

  • chain a, Structure Of An Indolicidin Peptide Derivative With

• • Source

  • Bos taurus (Bovine)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • ILKKWPWWPWRRKX

• • Sequence Length

  • 14

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacteria: Escherichia coli (MIC=8 µg/ml), Pseudomonas aeruginosa (MIC=16 µg/ml), Salmonella typhimurium (MIC=64 µg/ml), S. typhimurium defensin sensitive (MIC=2 µg/ml);
    • Gram-positive bacteria: Staphylococcus aureus (MIC=16 µg/ml), Staphylococcus aureus (MRSA) (MIC=16 µg/ml), S. epidermidis (MIC=4 µg/ml), Enterococcus faecalis (MIC>64 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Non helix or strand structure

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • 1QXQ resolved by NMR.
• 1QXQ-> 

• Predicted Structure

• There is no predicted structure for DRAMP02843.

DRAMP02843

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphosphocholine and sodium dodecyl sulfate micelles.

• • Pubmed ID

  • 11123901

• • Reference

  • Biochemistry. 2000 Dec 26;39(51):15765-15774.

• • Author

  • Rozek A, Friedrich CL, Hancock RE.