General Information
-
DRAMP ID
- DRAMP02881
-
Peptide Name
- Antimicrobial protein exons 1-2 (mammals, animals)
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Source
- Bos taurus (Bovine)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- NPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCR
-
Sequence Length
- 36
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal
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Target Organism
-
- Yeast: Candida ablicans.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- dulsulfide-bond link
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP02881.
Physicochemical Information
-
Formula
- C157H278N54O43S7
Absent Amino Acids
- DEFHLWY
Common Amino Acids
- C
Mass
- 3834.69
PI
- 9.7
Basic Residues
- 7
Acidic Residues
- 0
Hydrophobic Residues
- 9
Net Charge
- +7
-
Boman Index
- -53.96
Hydrophobicity
- 0.119
Aliphatic Index
- 75.56
Half Life
-
- Mammalian:1.4 hour
- Yeast:3 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 375
Absorbance 280nm
- 10.71
Polar Residues
- 15
DRAMP02881
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene.
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Pubmed ID
- 8506305
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Reference
- Proc Natl Acad Sci U S A. 1993 May 15;90(10):4596-600.
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Author
- Diamond G, Jones DE, Bevins CL.