• DRAMP ID

    • DRAMP02915
    • Peptide Name

    • Cathelicidin-2 (Bactenecin-5, Bac5; OaBac5; mammals, animals)
    • Source

    • Ovis aries (Sheep)
    • Family

    • Belongs to the cathelicidin family
    • Gene

    • CATHL2
    • Sequence

    • RFRPPIRRPPIRPPFRPPFRPPVRPPIRPPFRPPFRPPIGPFP
    • Sequence Length

    • 43
    • Protein Existence

    • Transcript level
    • Biological Activity

    • Antimicrobial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Lipipolysaccharides (LPS)-binding
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02915 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02915.
    • Formula

    • C251H384N76O44
    • Absent Amino Acids

    • ACDEHKLMNQSTWY
    • Common Amino Acids

    • P
    • Mass

    • 5170.29
    • PI

    • 13
    • Basic Residues

    • 11
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 11
    • Net Charge

    • +11
    • Boman Index

    • -121.58
    • Hydrophobicity

    • -0.998
    • Aliphatic Index

    • 43.02
    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 1

DRAMP02915

DRAMP02915 chydropathy plot
    • Function

    • Has potent antimicrobial activity (By similarity).
  • ·Literature 1
    • Title

    • Localization and genomic organization of sheep antimicrobial peptide genes.
    • Reference

    • Gene. 1998 Jan 5;206(1):85-91.
    • Author

    • Huttner KM, Lambeth MR, Burkin HR, Burkin DJ, Broad TE.