General Information
-
DRAMP ID
- DRAMP02921
-
Peptide Name
- Beta-defensin 138
-
Source
- Canis familiaris (Dog) (Canis lupus familiaris)
-
Family
- Not found
-
Gene
- CBD138
-
Sequence
- MRLLFLLFLLLVCLVQMTSGREKRRKSLECERMGGVCKHQKTHGCSILPAECKSRNKHCCRV
-
Sequence Length
- 62
-
UniProt Entry
- Q30KR8
-
Protein Existence
- Predicted
Activity Information
-
Biological Activity
- Antimicrobial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP02921.
Physicochemical Information
-
Formula
- C306H524N98O80S10
Absent Amino Acids
- DWY
Common Amino Acids
- L
Mass
- 7176.74
PI
- 9.72
Basic Residues
- 16
Acidic Residues
- 4
Hydrophobic Residues
- 18
Net Charge
- +12
-
Boman Index
- -117.6
Hydrophobicity
- -0.111
Aliphatic Index
- 89.52
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 375
Absorbance 280nm
- 6.15
Polar Residues
- 18
DRAMP02921
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
-
Pubmed ID
- 16033865
-
Reference
- Physiol Genomics. 2005 Sep 21;23(1):5-17.
-
Author
- Patil AA, Cai Y, Sang Y, Blecha F, Zhang G.