General Information

    • DRAMP ID

    • DRAMP02928

    • Peptide Name

    • Antibacterial 6.5 kDa protein (crabs, Arthropods, animals)

    • Source

    • Carcinus maenas (Common shore crab) (Green crab)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • XXVPYPRPFPRPPIGPRPLPFPGGGRPFQS

    • Sequence Length

    • 30

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • Psychrobacter immobilis, Micrococcus luteus, Escherichia coli D22.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02928 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02928.

Physicochemical Information

    • Formula

    • C148H215N41O30

    • Absent Amino Acids

    • ACDEHKMNTW

    • Common Amino Acids

    • P

    • Mass

    • 3307.28

    • PI

    • 12

    • Basic Residues

    • 4

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 6

    • Net Charge

    • +4

    • Boman Index

    • -42.18

    • Hydrophobicity

    • -0.73

    • Aliphatic Index

    • 35.67

    • Half Life

      • Mammalian:?
      • Yeast:?
      • E.coli:?

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 51.38

    • Polar Residues

    • 6

DRAMP02928

DRAMP02928 chydropathy plot

Comments Information

    • Function

    • Strong antimicrobial activity against Psychrobacter immobilis and M. luteus, less active against E. coli D22.

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterization of a proline-rich antibacterial peptide, with sequence similarity to bactenecin-7, from the haemocytes of the shore crab, Carcinus maenas.

    • Reference

    • Eur J Biochem. 1996 Sep 15;240(3):532-539.

    • Author

    • Schnapp D, Kemp GD, Smith VJ.