General Information
-
DRAMP ID
- DRAMP02947
-
Peptide Name
- PtALF2 (Portunus trituberculatus anti-lipopolysaccharide factor isoform 2; crabs, Arthropods, ani
-
Source
- Portunus trituberculatus (Swimming Crab)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- YEALVTSILGKLTGLWHNDSVDFMGHICYFRRRPKIRRFKLYHEGKFWCPGWAPFEGRSRTKSRSGSSREATKDFVRKALQNGLVTQQDASLWLN
-
Sequence Length
- 95
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Lipopolysaccharide (LPS)-binding
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP02947.
Physicochemical Information
-
Formula
- C501H770N148O134S3
Absent Amino Acids
- ?
Common Amino Acids
- RL
Mass
- 11106.72
PI
- 10.17
Basic Residues
- 20
Acidic Residues
- 8
Hydrophobic Residues
- 31
Net Charge
- +12
-
Boman Index
- -217.28
Hydrophobicity
- -0.622
Aliphatic Index
- 66.74
Half Life
-
- Mammalian:2.8 hour
- Yeast:10 min
- E.coli:2 min
Extinction Coefficient Cystines
- 26595
Absorbance 280nm
- 282.93
Polar Residues
- 29
DRAMP02947
Comments Information
Contains a signal peptide and an LPS-binding Domain
- (CYFRRRPKIRRFKLYHEGKFWC) and two conserved cysteine residues which can form a disulfide bridge.
Literature Information
- ·Literature 1
-
Title
- Three isoforms of anti-lipopolysaccharide factor identified from eyestalk cDNA library of swimming crab Portunus trituberculatus.
-
Pubmed ID
- 21168510
-
Reference
- Fish Shellfish Immunol. 2011 Feb;30(2):583-591.
-
Author
- Liu Y, Cui Z, Luan W, Song C, Nie Q, Wang S, Li Q.