General Information
-
DRAMP ID
- DRAMP02957
-
Peptide Name
- Liver-expressed antimicrobial protein 2 (pigs, mammals, animals)
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Source
- Sus scrofa (Pig)
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Family
- Not found
-
Gene
- Not found
-
Sequence
- MWHLKLFAVLVICLLLAVQVHGSPIPELSSAKRRPRRITPFWRAVSLRPIGASCRDDSECLTRLCRKRRCSLSVAQE
-
Sequence Length
- 77
-
UniProt Entry
- Q8MJ79
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Protein Existence
- Predicted
Activity Information
-
Biological Activity
- Antimicrobial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP02957.
Physicochemical Information
-
Formula
- C388H647N121O100S6
Absent Amino Acids
- NY
Common Amino Acids
- LR
Mass
- 8799.52
PI
- 10.73
Basic Residues
- 16
Acidic Residues
- 5
Hydrophobic Residues
- 31
Net Charge
- +11
-
Boman Index
- -141.23
Hydrophobicity
- 0.069
Aliphatic Index
- 106.36
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 11250
Absorbance 280nm
- 148.03
Polar Residues
- 17
DRAMP02957
![DRAMP02957 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP02957.1.png)
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Porcine liver-expressed antimicrobial peptides, hepcidin and LEAP-2: cloning and induction by bacterial infection.
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Pubmed ID
- 16051358
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Reference
- Dev Comp Immunol. 2006;30(4):357-366.
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Author
- Sang Y, Ramanathan B, Minton JE, Ross CR, Blecha F.