General Information
-
DRAMP ID
- DRAMP02958
-
Peptide Name
- Cathelin (pigs, mammals, animals)
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Source
- Sus scrofa (Pig)
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Family
- Belongs to the cathelicidin family
-
Gene
- Not found
-
Sequence
- QLRYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKEKQCVGTVTLNPSIHSLDISCNEIQSV
-
Sequence Length
- 96
-
UniProt Entry
- P15175
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Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Unknown
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP02958.
Physicochemical Information
-
Formula
- C470H762N134O152S4
Absent Amino Acids
- MW
Common Amino Acids
- LPE
Mass
- 10850.27
PI
- 5.11
Basic Residues
- 13
Acidic Residues
- 15
Hydrophobic Residues
- 27
Net Charge
- -2
-
Boman Index
- -233.28
Hydrophobicity
- -0.656
Aliphatic Index
- 81.15
Half Life
-
- Mammalian:0.8 hour
- Yeast:10 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 3230
Absorbance 280nm
- 34
Polar Residues
- 25
DRAMP02958
Comments Information
Function
- Probably a microbicidal peptide.
PTM
- contains two disulfide bonds 55-66; 73-90.
Literature Information
- ·Literature 1
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Title
- Pig leukocyte cysteine proteinase inhibitor (PLCPI), a new member of the stefin family.
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Pubmed ID
- 8262248
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Reference
- FEBS Lett. 1993 Dec 27;336(2):289-292.
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Author
- Lenarcic B, Ritonja A, Dolenc I, Stoka V, Berbic S, Pungercar J, Strukelj B, Turk V.