• DRAMP ID

    • DRAMP02996
    • Peptide Name

    • Apidaecin-2 (Apidaecin II; Insects, animals)
    • Source

    • Apis mellifera (Honeybee)
    • Family

    • Belongs to the apidaecin family
    • Gene

    • APID14
    • Sequence

    • GNNRPIYIPQPRPPHPRL
    • Sequence Length

    • 18
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-negative bacteria: Agrobacterium tumefaciens (MIC=0.2 µg/ml), Erwinia salicis (MIC=0.02 µg/ml), Escherichia coli (MIC=0.2 µg/ml), Pseudomonas syringae (MIC=0.1 µg/ml), Rhizobium meliloti (MIC=0.02 µg/ml), Salmonella Newport (MIC=0.2 µg/ml), Salmonella typhimurium (MIC=0.1 µg/ml);
      • Gram-positive bacteria: Shigella flexneri (MIC=0.1 µg/ml), Corynebacterium insidiosum (MIC=100 µg/ml), Bacillus megaterium (MIC=100 µg/ml)
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02996 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02996.
    • Formula

    • C96H152N32O23
    • Absent Amino Acids

    • ACDEFKMSTVW
    • Common Amino Acids

    • P
    • Mass

    • 2122.46
    • PI

    • 11.71
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 3
    • Net Charge

    • +4
    • Boman Index

    • -52.68
    • Hydrophobicity

    • -1.428
    • Aliphatic Index

    • 65
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1490
    • Absorbance 280nm

    • 87.65
    • Polar Residues

    • 4

DRAMP02996

DRAMP02996 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Apidaecins: antibacterial peptides from honeybees.
    • Reference

    • EMBO J. 1989 Aug;8(8):2387-2391.
    • Author

    • Casteels P, Ampe C, Jacobs F, Vaeck M, Tempst P.