• • DRAMP ID

  • DRAMP03021

• • Peptide Name

  • Mastoparan PMM

• • Source

  • Polistes major major

• • Family

  • Belongs to the mastoparan family

• • Gene

  • Not found

• • Sequence

  • INWKKIASIGKEVLKAL

• • Sequence Length

  • 17

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.18375018]Gram-positive bacterium: Bacillus subtilis (MIC=7.3 µM);
    • Gram-negative bacterium: Escherichia coli (MIC=25.8 µM).

• • Hemolytic Activity

  • • [Ref.18375018]IC50=80 μM against rat red blood cells

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP03021_predicted_structure.pdb to download.

DRAMP03021

• • Function

  • Has antibacterial activity. Shows hemolytic activity.

• ·Literature 1

• • Title

  • New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs.

• • Pubmed ID

  • 18375018

• • Reference

  • Peptides. 2008 Jun;29(6):992-1003.

• • Author

  • Cerovský V, Slaninová J, Fucík V, Hulacová H, Borovicková L, Jezek R, Bednárová L.