• DRAMP ID

    • DRAMP03022
    • Peptide Name

    • Mastoparan MP
    • Source

    • Mischocyttarus phthisicus
    • Family

    • Belongs to the mastoparan family
    • Gene

    • Not found
    • Sequence

    • INWLKLGKKMMSAL
    • Sequence Length

    • 14
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • [Ref.18375018]Gram-positive bacterium: Bacillus subtilis (MIC=9 µM);
      • Gram-negative bacterium: Escherichia coli (MIC=65 µM).
    • Hemolytic Activity

      • [Ref.18375018]IC50=100 μM against rat red blood cells
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03022 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • Formula

    • C75H129N19O17S2
    • Absent Amino Acids

    • CDEFHPQRTVY
    • Common Amino Acids

    • KL
    • Mass

    • 1633.09
    • PI

    • 10.3
    • Basic Residues

    • 3
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 6
    • Net Charge

    • +3
    • Boman Index

    • 2.77
    • Hydrophobicity

    • 0.3
    • Aliphatic Index

    • 118.57
    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 423.08
    • Polar Residues

    • 3

DRAMP03022

    • Function

    • Has antibacterial activity. Has hemolytic activity.
  • ·Literature 1
    • Title

    • New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs.
    • Reference

    • Peptides. 2008 Jun;29(6):992-1003.
    • Author

    • Cerovský V, Slaninová J, Fucík V, Hulacová H, Borovicková L, Jezek R, Bednárová L.