• DRAMP ID

    • DRAMP03032
    • Peptide Name

    • Mastoparan-A (Insects, animals)
    • Source

    • Vespa analis (Yellow-vented hornet)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • IKWKAILDAVKKVL
    • Sequence Length

    • 14
    • Protein Existence

    • Transcript level
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03032 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03032.
    • Formula

    • C79H137N19O17
    • Absent Amino Acids

    • CEFGHMNPQRSTY
    • Common Amino Acids

    • K
    • Mass

    • 1625.07
    • PI

    • 10
    • Basic Residues

    • 4
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 9
    • Net Charge

    • +3
    • Boman Index

    • 2.79
    • Hydrophobicity

    • 0.614
    • Aliphatic Index

    • 167.14
    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 423.08
    • Polar Residues

    • 0

DRAMP03032

    • Function

    • Chemotactic peptide for polymorphonucleated leukocytes (PMNL), but causing no hemolysis to erythrocytes and no mast cell degranulation activity at physiological concentrations. Potent antimicrobial peptide against both Gram-positive and Gram-negative bacteria.
    • Tissue specificity

    • Expressed by the venom gland.
    • PTM

    • C-terminal amidation (Leucine amide
  • ·Literature 1
    • Title

    • Inflammatory role of two venom components of yellow jackets (Vespula vulgaris): a mast cell degranulating peptide mastoparan and phospholipase A1.
    • Reference

    • Int Arch Allergy Immunol. 2003 May;131(1):25-32.
    • Author

    • King T.P, Jim S.Y, Wittkowski K.M.