• • DRAMP ID

  • DRAMP03035

• • Peptide Name

  • Mastoparan-like peptide 12c (Insects, animals)

• • Source

  • Vespa magnifica (Hornet)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • INLKAIAALAKKLLG

• • Sequence Length

  • 15

• • UniProt Entry

  • A0SPI0

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.0 µg/ml);
    • Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=3.0 µg/ml).
    • Fungi: Candida albicans ATCC 2002 (MIC=12.0 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP03035_predicted_structure.pdb to download.

DRAMP03035

• • Function

  • Shows mast cell degranulation and antimicrobial activities.

• • Tissue specificity

  • Expressed by the venom gland.

• • PTM

  • C-terminal amidation (Leucine amide

• ·Literature 1

• • Title

  • The mastoparanogen from wasp.

• • Pubmed ID

  • 17046111

• • Reference

  • Peptides. 2006 Dec;27(12):3053-3057.

• • Author

  • Xu X, Yang H, Yu H, Li J, Lai R.