General Information

    • DRAMP ID

    • DRAMP03068

    • Peptide Name

    • Antifungal protein 1 (MAF-1; Insects, animals)

    • Source

    • Musca domestica (House fly)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ESAPAPEVSGDAVFSAIQNGXLKNLGNAFFW

    • Sequence Length

    • 31

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03068 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03068.

Physicochemical Information

    • Formula

    • C143H208N36O43

    • Absent Amino Acids

    • CHMRTY

    • Common Amino Acids

    • A

    • Mass

    • 3248.79

    • PI

    • 4.14

    • Basic Residues

    • 1

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 14

    • Net Charge

    • -2

    • Boman Index

    • -17.57

    • Hydrophobicity

    • 0.058

    • Aliphatic Index

    • 72.58

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 183.33

    • Polar Residues

    • 9

DRAMP03068

DRAMP03068 chydropathy plot

Comments Information

    • Function

    • Antifungal activity against C.albicans ATCC 76615.

Literature Information

  • ·Literature 1

    • Title

    • Purification and molecular identification of an antifungal peptide from the hemolymph of Musca domestica (housefly).

    • Reference

    • Cell Mol Immunol. 2009 Aug;6(4):245-251.

    • Author

    • Fu P, Wu J, Guo G.