General Information

    • DRAMP ID

    • DRAMP03099

    • Peptide Name

    • Attacin-C (Insects, animals)

    • Source

    • Drosophila melanogaster (Fruit fly)

    • Family

    • Not found

    • Gene

    • AttC

    • Sequence

    • QRPYTQPLIYYPPPPTPPRIYRA

    • Sequence Length

    • 23

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Target Organism

    • Agrobacterium tumefaciens (MIC>200 µM), Enterobacter cloacae b12 (MIC>200 µM), Escherichia coli SBS 363 (MIC>200 µM), Escherichia coli D31 (MIC>=200 µM), Escherichia coli D22 (MIC>=200 µM), Erwinia carotovora carotovora (MIC>200 µM), Pseudomonas aeruginosa (MIC>200 µM), Salmonella typhimurium (MIC>200 µM), Serratia marcescens (MIC>200 µM), Bacillus megaterium (MIC>200 µM), Micrococcus luteus(MIC>200 µM), Staphylococcus aureus (MIC>200 µM), Streptococcus pyogenes (MIC>200 µM), Neurospora crassa (MIC>200 µM), Aspergillus fumigatus (MIC>200 µM), Candida albicans (MIC>200 µM), Candida glabrata (MIC>200 µM), Cryptococcus neoformans (MIC>200 µM), Saccharomyces cerevisiae (MIC>200 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Rich

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03099 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03099.

Physicochemical Information

    • Formula

    • C133H198N34O32

    • Absent Amino Acids

    • CDEFGHKMNSVW

    • Common Amino Acids

    • P

    • Mass

    • 2785.24

    • PI

    • 9.99

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 4

    • Net Charge

    • +3

    • Boman Index

    • -44.97

    • Hydrophobicity

    • -1.1

    • Aliphatic Index

    • 55.22

    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5960

    • Absorbance 280nm

    • 270.91

    • Polar Residues

    • 6

DRAMP03099

DRAMP03099 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Primary structure and in vitro antibacterial properties of the Drosophila melanogaster attacin C Pro-domain.

    • Reference

    • J Biol Chem. 2004 Apr 9;279(15):14853-9. Epub 2004 Jan 26.

    • Author

    • Rabel D, Charlet M, Ehret-Sabatier L, Cavicchioli L, Cudic M, Otvos L Jr, Bulet P.