General Information
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP03123.
Physicochemical Information
-
Formula
- C181H298N54O39
Absent Amino Acids
- CDHMQST
Common Amino Acids
- AK
Mass
- 3854.7
PI
- 11.61
Basic Residues
- 10
Acidic Residues
- 1
Hydrophobic Residues
- 16
Net Charge
- +9
-
Boman Index
- -51.92
Hydrophobicity
- -0.309
Aliphatic Index
- 92.06
Half Life
-
- Mammalian:4.4 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 6990
Absorbance 280nm
- 211.82
Polar Residues
- 5
DRAMP03123
Comments Information
Function
- Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria (By similarity).
Literature Information
- ·Literature 1
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Title
- Genomic organization and regulation of three cecropin genes in Anopheles gambiae.
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Pubmed ID
- 12421409
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Reference
- Insect Mol Biol. 2002 Dec;11(6):517-525.
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Author
- Zheng XL, Zheng AL.