• DRAMP ID

    • DRAMP03131
    • Peptide Name

    • Cecropin-B (Insects, animals)
    • Source

    • Aedes albopictus (Asian tiger mosquito)
    • Family

    • Belongs to the cecropin family
    • Gene

    • CECB1 AND CECB2
    • Sequence

    • GGLKKLGKKLEGVGKRVFKASEKALPVLTGYKAIG
    • Sequence Length

    • 35
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03131 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03131.
    • Formula

    • C168H290N46O43
    • Absent Amino Acids

    • CDHMNQW
    • Common Amino Acids

    • K
    • Mass

    • 3642.43
    • PI

    • 10.3
    • Basic Residues

    • 9
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 13
    • Net Charge

    • +7
    • Boman Index

    • -22.42
    • Hydrophobicity

    • -0.16
    • Aliphatic Index

    • 100.29
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1490
    • Absorbance 280nm

    • 43.82
    • Polar Residues

    • 10

DRAMP03131

DRAMP03131 chydropathy plot
    • Function

    • Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria (By similarity)
    • Developmental stage

    • Expressed within 2 hours after induction and continued to accumulate over 24 hours.
    • Induction

    • By bacterial infection.
  • ·Literature 1
    • Title

    • Cloning and expression of three cecropin cDNAs from a mosquito cell line.
    • Reference

    • FEBS Lett. 1999; 454:147-151.
    • Author

    • Sun D, Eccleston ED, Fallon AM.