General Information

    • DRAMP ID

    • DRAMP03132

    • Peptide Name

    • Cecropin-C (Insects, animals)

    • Source

    • Aedes albopictus (Asian tiger mosquito)

    • Family

    • Belongs to the cecropin family

    • Gene

    • CECC1 AND CECC2

    • Sequence

    • GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKALG

    • Sequence Length

    • 35

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03132 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03132.

Physicochemical Information

    • Formula

    • C156H272N46O41

    • Absent Amino Acids

    • CDHIMQSTWY

    • Common Amino Acids

    • AGK

    • Mass

    • 3448.16

    • PI

    • 10.39

    • Basic Residues

    • 8

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 16

    • Net Charge

    • +6

    • Boman Index

    • -15.08

    • Hydrophobicity

    • 0.009

    • Aliphatic Index

    • 100.57

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 8

DRAMP03132

DRAMP03132 chydropathy plot

Comments Information

    • Function

    • Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.

    • Reference

    • Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.

    • Author

    • sir YJ, Knoop FC, Dulka J, Conlon JM.