General Information

    • DRAMP ID

    • DRAMP03144

    • Peptide Name

    • Salivary defensin

    • Source

    • Anopheles stephensi (Indo-Pakistan malaria mosquito)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ATCDLASGFGVGSSLCAAHCIARRYRGGYCNSQQVCVCRN

    • Sequence Length

    • 40

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03144 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03144.

Physicochemical Information

    • Formula

    • C171H274N58O54S6

    • Absent Amino Acids

    • EKMPW

    • Common Amino Acids

    • C

    • Mass

    • 4198.77

    • PI

    • 8.69

    • Basic Residues

    • 5

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +4

    • Boman Index

    • -62.58

    • Hydrophobicity

    • 0.108

    • Aliphatic Index

    • 63.5

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 3355

    • Absorbance 280nm

    • 86.03

    • Polar Residues

    • 20

DRAMP03144

DRAMP03144 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Molecular and phylogenetic analysis of a novel salivary defensin cDNA from malaria vector Anopheles stephensi.

    • Reference

    • Acta Trop. 2008 Apr;106(1):75-79.

    • Author

    • Dixit R, Sharma A, Patole MS, Shouche YS.