General Information

    • DRAMP ID

    • DRAMP03147

    • Peptide Name

    • Defensin-A

    • Source

    • Culex quinquefasciatus (Southern house mosquito) (Culex pungens)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ATCDLLSGLGVNDSACAAHCIARGNRGGYCNSKKVCVCRN

    • Sequence Length

    • 40

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03147 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03147.

Physicochemical Information

    • Formula

    • C164H275N57O54S6

    • Absent Amino Acids

    • EFMPQW

    • Common Amino Acids

    • C

    • Mass

    • 4101.7

    • PI

    • 8.68

    • Basic Residues

    • 6

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +4

    • Boman Index

    • -64.2

    • Hydrophobicity

    • 0.015

    • Aliphatic Index

    • 73.25

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1865

    • Absorbance 280nm

    • 47.82

    • Polar Residues

    • 20

DRAMP03147

DRAMP03147 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Annotation of Culex pipiens quinquefasciatus.

    • Reference

    • Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases

    • Author

    • The Broad Institute Genome Sequencing Platform.