• • DRAMP ID

  • DRAMP03158

• • Peptide Name

  • Halocidin subunit A (invertebrates, animals; Preclinical)

• • Source

  • Halocynthia aurantium (Sea peach)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • WLNALLHHGLNCAKGVLA

• • Sequence Length

  • 18

• • UniProt Entry

  • P83705

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-positive bacterium: Staphylococcus aureus;
    • Gram-negative bacterium: Pseudomonas aeruginosa.

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP03158.

DRAMP03158

• • Function

  • Antimicrobial activity against S.aureus and P.aeruginosa, possibly by attacking the bacterial cell membrane. Mouse model

• ·Literature 1

• • Title

  • Halocidin: a new antimicrobial peptide from hemocytes of the solitary tunicate, Halocynthia aurantium.

• • Pubmed ID

  • 12067731

• • Reference

  • FEBS Lett. 2002 Jun 19;521(1-3):81-86.

• • Author

  • Jang WS, Kim KN, Lee YS, Nam MH, Lee IH.