General Information
-
DRAMP ID
- DRAMP03170
-
Peptide Name
- Antibacterial protein 1 homolog (Gram-positive bacteria)
-
Source
- Staphylococcus haemolyticus (strain JCSC1435)
-
Family
- Belongs to the staphylococcal hemolytic protein family
-
Gene
- Not found
-
Sequence
- MQKLAEAIAAAVQAGQDKDWGKMGTSIVGIVENGISVLGKIFGF
-
Sequence Length
- 44
-
UniProt Entry
- Q4L5M5
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- Gonococci
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03170.
Physicochemical Information
-
Formula
- C204H331N53O60S2
Absent Amino Acids
- CHPRY
Common Amino Acids
- G
Mass
- 4550.31
PI
- 5.97
Basic Residues
- 4
Acidic Residues
- 4
Hydrophobic Residues
- 20
Net Charge
- 0
-
Boman Index
- -4.86
Hydrophobicity
- 0.398
Aliphatic Index
- 102.05
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 127.91
Polar Residues
- 11
DRAMP03170
Comments Information
Function
- Has haemolytic activity and also inhibits the growth of gonococci (By similarity).
Literature Information
- ·Literature 1
-
Title
- Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species.
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Pubmed ID
- 16237012
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Reference
- J Bacteriol. 2005 Nov;187(21):7292-7308.
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Author
- Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K.