• DRAMP ID

    • DRAMP03223
    • Peptide Name

    • M-ctenitoxin-Cs1b (M-CNTX-Cs1b; Cupiennin-1b; spiders, Arthropods, animals)
    • Source

    • Cupiennius salei (Wandering spider)
    • Family

    • Belongs to the cupiennin family
    • Gene

    • Not found
    • Sequence

    • GFGSLFKFLAKKVAKTVAKQAAKQGAKYIANKQME
    • Sequence Length

    • 35
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Insecticidal
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • [Ref.11792701]Not determined
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Serum or Protease Type

    • Not available
    • Stability Data

    • Not available
    • Assay

    • Not available
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03223 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03223.
    • Formula

    • C175H287N47O45S
    • Absent Amino Acids

    • CDHPRW
    • Common Amino Acids

    • K
    • Mass

    • 3801.55
    • PI

    • 10.3
    • Basic Residues

    • 8
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 15
    • Net Charge

    • +7
    • Boman Index

    • -30.96
    • Hydrophobicity

    • -0.266
    • Aliphatic Index

    • 70
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1490
    • Absorbance 280nm

    • 43.82
    • Polar Residues

    • 7

DRAMP03223

DRAMP03223 chydropathy plot
    • Function

    • Has antimicrobial activity. Has insecticidal activity. Probably acts by disturbing membrane Function
  • ·Literature 1
    • Title

    • Cupiennin 1, a new family of highly basic antimicrobial peptides in the venom of the spider Cupiennius salei (Ctenidae).
    • Reference

    • J Biol Chem. 2002 Mar 29;277(13):11208-11216.
    • Author

    • Kuhn-Nentwig L, Muller J, Schaller J, Walz A, Dathe M, Nentwig W.