General Information

    • DRAMP ID

    • DRAMP03258

    • Peptide Name

    • Rondonin (spiders, Arthropods, animals)

    • Source

    • Acanthoscurria rondoniae (Spider)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • IIIQYEGHKH

    • Sequence Length

    • 10

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • [Swiss_Prot Entry B3EWP8]Non-hemolytic activity

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03258 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03258.

Physicochemical Information

    • Formula

    • C57H88N16O15

    • Absent Amino Acids

    • ACDFLMNPRSTVW

    • Common Amino Acids

    • I

    • Mass

    • 1237.42

    • PI

    • 6.92

    • Basic Residues

    • 3

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 3

    • Net Charge

    • +2

    • Boman Index

    • -11.66

    • Hydrophobicity

    • -0.55

    • Aliphatic Index

    • 117

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 165.56

    • Polar Residues

    • 2

DRAMP03258

Comments Information

    • Function

    • Exhibits antifungal activity against Candida sp. No hemolytic activity

Literature Information

  • ·Literature 1

    • Title

    • Rondonin an antifungal peptide from spider (Acanthoscurria rondoniae) haemolymph.

    • Reference

    • Results Immunol. 2012;2:66-71.

    • Author

    • Riciluca K.C.T, Sayegh R.S.R, Melo R.L, Silva P.I. Jr.