General Information
-
DRAMP ID
- DRAMP03271
-
Peptide Name
- U15-lycotoxin-Ls1c (Toxin-like structure LSTX-N12; spiders, Arthropods, animals)
-
Source
- Lycosa singoriensis (Wolf spider) (Aranea singoriensis)
-
Family
- Spider wap-1 family (Contains 1 WAP domain)
-
Gene
- Not found
-
Sequence
- DQYCPKSSITACKKMNIRNDCCKDDDCTGGSWCCATPCGNICKYPTDRPGGKRAAGGKSCKTGYVY
-
Sequence Length
- 66
-
UniProt Entry
- B6DD45
-
Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03271.
Physicochemical Information
-
Formula
- C292H464N88O96S11
Absent Amino Acids
- EFHL
Common Amino Acids
- C
Mass
- 7096.09
PI
- 8.72
Basic Residues
- 11
Acidic Residues
- 6
Hydrophobic Residues
- 9
Net Charge
- +5
-
Boman Index
- -142.91
Hydrophobicity
- -0.762
Aliphatic Index
- 28.18
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 12085
Absorbance 280nm
- 185.92
Polar Residues
- 34
DRAMP03271
Comments Information
Function
- Has antibacterial activity (By similarity).
Tissue specificity
- Expressed by the venom gland.
PTM
- Contains four disulfide bonds (Probable).
Literature Information
- ·Literature 1
-
Title
- Transcriptome analysis of the venom glands of the Chinese wolf spider Lycosa singoriensis.
-
Pubmed ID
- 19875276
-
Reference
- Zoology (Jena). 2010 Jan;113(1):10-18.
-
Author
- hang Y, Chen J, Tang X, Wang F, Jiang L, Xiong X, Wang M, Rong M, Liu Z, Liang S.