General Information
-
DRAMP ID
- DRAMP03277
-
Peptide Name
- U15-lycotoxin-Ls1h (Toxin-like structure LSTX-N18; spiders, Arthropods, animals)
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Source
- Lycosa singoriensis (Wolf spider) (Aranea singoriensis)
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Family
- Spider wap-1 family (Contains 1 WAP domain)
-
Gene
- Not found
-
Sequence
- DQYCPKSSITACKKMNTRNDCCKDDDCTGGSWCCATPCGNFCKYPTDRPGGKRAAGGKSCKTGYVYY
-
Sequence Length
- 67
-
UniProt Entry
- B6DD51
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Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP03277.
Physicochemical Information
-
Formula
- C302H467N89O99S11
Absent Amino Acids
- EHL
Common Amino Acids
- C
Mass
- 7281.23
PI
- 8.71
Basic Residues
- 11
Acidic Residues
- 6
Hydrophobic Residues
- 8
Net Charge
- +5
-
Boman Index
- -152.48
Hydrophobicity
- -0.873
Aliphatic Index
- 16.12
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 13575
Absorbance 280nm
- 205.68
Polar Residues
- 36
DRAMP03277
![DRAMP03277 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP03277.1.png)
Comments Information
Function
- Has antibacterial activity (By similarity).
Tissue specificity
- Expressed by the venom gland.
PTM
- Contains four disulfide bonds (Probable).
Literature Information
- ·Literature 1
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Title
- Transcriptome analysis of the venom glands of the Chinese wolf spider Lycosa singoriensis.
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Pubmed ID
- 19875276
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Reference
- Zoology (Jena). 2010 Jan;113(1):10-18.
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Author
- hang Y, Chen J, Tang X, Wang F, Jiang L, Xiong X, Wang M, Rong M, Liu Z, Liang S.