General Information
-
DRAMP ID
- DRAMP03284
-
Peptide Name
- Beta-defensin (Birds, animals)
-
Source
- Dromaius novaehollandiae (Emu)
-
Family
- Belongs to the beta-defensin family
-
Gene
- Not found
-
Sequence
- LPRHTLHCVAYHGYCFHSKV
-
Sequence Length
- 20
-
UniProt Entry
- P86385
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP03284.
Physicochemical Information
-
Formula
- C108H158N32O25S2
Absent Amino Acids
- DEIMNQW
Common Amino Acids
- H
Mass
- 2368.76
PI
- 8.86
Basic Residues
- 6
Acidic Residues
- 0
Hydrophobic Residues
- 6
Net Charge
- +6
-
Boman Index
- -19.15
Hydrophobicity
- -0.085
Aliphatic Index
- 73
Half Life
-
- Mammalian:5.5 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 3105
Absorbance 280nm
- 163.42
Polar Residues
- 7
DRAMP03284
![DRAMP03284 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP03284.1.png)
Comments Information
Function
- Has bactericidal activity (By similarity).
Literature Information
- ·Literature 1
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Title
- Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white.
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Pubmed ID
- 22044478
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Reference
- Gene. 2012 Jan 15;492(1):244-249.
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Author
- Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T.