General Information

    • DRAMP ID

    • DRAMP03284

    • Peptide Name

    • Beta-defensin (Birds, animals)

    • Source

    • Dromaius novaehollandiae (Emu)

    • Family

    • Belongs to the beta-defensin family

    • Gene

    • Not found

    • Sequence

    • LPRHTLHCVAYHGYCFHSKV

    • Sequence Length

    • 20

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03284 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03284.

Physicochemical Information

    • Formula

    • C108H158N32O25S2

    • Absent Amino Acids

    • DEIMNQW

    • Common Amino Acids

    • H

    • Mass

    • 2368.76

    • PI

    • 8.86

    • Basic Residues

    • 6

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 6

    • Net Charge

    • +6

    • Boman Index

    • -19.15

    • Hydrophobicity

    • -0.085

    • Aliphatic Index

    • 73

    • Half Life

      • Mammalian:5.5 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 3105

    • Absorbance 280nm

    • 163.42

    • Polar Residues

    • 7

DRAMP03284

DRAMP03284 chydropathy plot

Comments Information

    • Function

    • Has bactericidal activity (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white.

    • Reference

    • Gene. 2012 Jan 15;492(1):244-249.

    • Author

    • Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T.