General Information
-
DRAMP ID
- DRAMP03313
-
Peptide Name
- Metalnikowin-2A (Metalnikowin IIA; Insects, animals)
-
Source
- Palomena prasina (Green shield bug) (Cimex prasinus)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- VDKPDYRPRPWPRPN
-
Sequence Length
- 15
-
UniProt Entry
- P80409
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03313.
Physicochemical Information
-
Formula
- C86H129N27O22
Absent Amino Acids
- ACEFGHILMQST
Common Amino Acids
- P
Mass
- 1893.14
PI
- 9.98
Basic Residues
- 4
Acidic Residues
- 2
Hydrophobic Residues
- 2
Net Charge
- +2
-
Boman Index
- -68.16
Hydrophobicity
- -2.26
Aliphatic Index
- 19.33
Half Life
-
- Mammalian:100 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 6990
Absorbance 280nm
- 499.29
Polar Residues
- 2
DRAMP03313
Comments Information
Function
- Antibacterial peptide active against Gram-negative bacteria.
Induction
- By bacterial infection.
Literature Information
- ·Literature 1
-
Title
- The inducible antibacterial peptides of the hemipteran insect Palomena prasina: identification of a unique family of proline-rich peptides and of a novel insect defensin.
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Pubmed ID
- PubMed ID is not available
-
Reference
- J. Insect Physiol. 1996; 42: 81-89.
-
Author
- Chernysh S, Cociancich S, Briand JP, Hetru C, Bulet P.