General Information

    • DRAMP ID

    • DRAMP03321

    • Peptide Name

    • Colutellin-A

    • Source

    • Colletotrichum dematium (Anthracnose fungus)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • VISIIPV

    • Sequence Length

    • 7

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Sclerotinia sclerotiorum (MIC=32.4 µg/ml after 288 hours), Botrytis cinerea (MIC=10.8 µg/ml after 288 hours),Fusarium solani, Aspergillus fumigatus, Geotrichum candidum.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • [Ref.18599825] It has less cytotoxicity against human PBMCs.

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Cyclic

    • N-terminal Modification

    • No specific N-terminal

    • C-terminal Modification

    • No specific C-terminal

    • Nonterminal Modifications and Unusual Amino Acids

    • Free

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03321 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03321.

Physicochemical Information

    • Formula

    • C36H65N7O9

    • Absent Amino Acids

    • ACDEFGHKLMNQRTWY

    • Common Amino Acids

    • I

    • Mass

    • 739.95

    • PI

    • 5.49

    • Basic Residues

    • 0

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • 0

    • Boman Index

    • 19.44

    • Hydrophobicity

    • 2.786

    • Aliphatic Index

    • 250

    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 1

DRAMP03321

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Colutellin A, an immunosuppressive peptide from Colletotrichum dematium.

    • Reference

    • Microbiology. 2008 Jul;154(Pt 7):1973-1979.

    • Author

    • Ren Y, Strobel GA, Graff JC, Jutila M, Park SG, Gosh S, Teplow D, Condron M, Pang E, Hess WM, Moore E.