• DRAMP ID

    • DRAMP03382
    • Peptide Name

    • Beta-defensin 18 (BD-18, mBD-18; Defensin, beta 18; Rodents, mammals, animals)
    • Source

    • Mus musculus (Mouse)
    • Family

    • Belongs to the beta-defensin family
    • Gene

    • Defb18
    • Sequence

    • APQMKTREVAERTHKCSLVRGTCKSECNSWEYKYNYCHTEPCCVVREYKRMEKLLSTPKYTT
    • Sequence Length

    • 62
    • Protein Existence

    • Homology
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Bridge
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03382 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03382.
    • Formula

    • C317H504N92O96S8
    • Absent Amino Acids

    • DFI
    • Common Amino Acids

    • EKTC
    • Mass

    • 7396.53
    • PI

    • 8.99
    • Basic Residues

    • 14
    • Acidic Residues

    • 7
    • Hydrophobic Residues

    • 10
    • Net Charge

    • +7
    • Boman Index

    • -171.36
    • Hydrophobicity

    • -0.989
    • Aliphatic Index

    • 40.81
    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 13325
    • Absorbance 280nm

    • 218.44
    • Polar Residues

    • 25

DRAMP03382

DRAMP03382 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
    • Reference

    • Physiol Genomics. 2005 Sep 21;23(1):5-17.
    • Author

    • Patil A.A, Cai Y, Sang Y, Blecha F, Zhang G.