General Information

    • DRAMP ID

    • DRAMP03404

    • Peptide Name

    • Cramp 18 (CRAMP analogue)

    • Source

    • Mus musculus (Mouse)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GEKLKKIGQKIKNFFQKL

    • Sequence Length

    • 18

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Not found

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03404 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03404.

Physicochemical Information

    • Formula

    • C101H171N27O24

    • Absent Amino Acids

    • ACDHMPRSTVWY

    • Common Amino Acids

    • K

    • Mass

    • 2147.64

    • PI

    • 10.3

    • Basic Residues

    • 6

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 6

    • Net Charge

    • +5

    • Boman Index

    • -30.31

    • Hydrophobicity

    • -0.889

    • Aliphatic Index

    • 86.67

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP03404

DRAMP03404 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • CRAMP Analogues Having Potent Antibiotic Activity against Bacterial, Fungal, and Tumor Cells without Hemolytic Activity.

    • Reference

    • Biochem Biophys Res Commun. 2000 Sep 7;275(3):904-909.

    • Author

    • Shin SY, Kang SW, Lee DG, Eom SH, Song WK, Kim JI.