General Information

    • DRAMP ID

    • DRAMP03468

    • Peptide Name

    • Alveolarin (Fungus)

    • Source

    • Polyporus alveolaris (Hexagonal-pored polypore) (Favolus alveolaris)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GVCDMADLA

    • Sequence Length

    • 9

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Botrytis cinerea, Fusarium oxysporum, Mycosphaerella arachidicola and Physalospora piricola.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03468 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03468.

Physicochemical Information

    • Formula

    • C35H59N9O14S2

    • Absent Amino Acids

    • EFHIKNPQRSTWY

    • Common Amino Acids

    • AD

    • Mass

    • 894.03

    • PI

    • 3.56

    • Basic Residues

    • 0

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 4

    • Net Charge

    • -2

    • Boman Index

    • -0.29

    • Hydrophobicity

    • 0.956

    • Aliphatic Index

    • 97.78

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 2

DRAMP03468

Comments Information

    • Function

    • Antifungal activity. Inhibits mycelial growth of F. cinera, F. oxysporum, M. arachidicola and P. piricola. Lacks protease, ribonuclease, deoxyribonuclease and hemagglutinating activity.

Literature Information

  • ·Literature 1

    • Title

    • Alveolarin, a novel antifungal polypeptide from the wild mushroom Polyporus alveolaris.

    • Reference

    • Peptides. 2004 Apr;25(4):693-696.

    • Author

    • Wang H, Ng TB, Liu Q.