General Information

    • DRAMP ID

    • DRAMP03474

    • Peptide Name

    • Pleurostatin (Fungus)

    • Source

    • Pleurotus ostreatus (Oyster mushroom)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • VRPYLVAF

    • Sequence Length

    • 8

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • 20% growth inhibition Fusarium oxysporum (MIC=15.6 µM).##45% growth inhibition Mycosphaerella arachidicola (MIC=15.6 µM).##63% growth inhibition Physalospora piricola (MIC=15.6 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • Free

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03474 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03474.

Physicochemical Information

    • Formula

    • C48H73N11O10

    • Absent Amino Acids

    • CDEGHIKMNQSTW

    • Common Amino Acids

    • V

    • Mass

    • 964.18

    • PI

    • 8.72

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +1

    • Boman Index

    • 2.73

    • Hydrophobicity

    • 1.175

    • Aliphatic Index

    • 133.75

    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 212.86

    • Polar Residues

    • 1

DRAMP03474

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Pleurostrin, an antifungal peptide from the oyster mushroom

    • Reference

    • Peptides. 2005 Nov;26(11):2098-103. Epub 2005 Jun 6.

    • Author

    • Chu K.T, Xia L, Ng T.B.