General Information

    • DRAMP ID

    • DRAMP03487

    • Peptide Name

    • Lebocin Peptide 1A (LP1A; Insects, animals)

    • Source

    • Manduca sexta

    • Family

    • Belongs to the cecropin family

    • Gene

    • Not found

    • Sequence

    • QRFSQPTFKLPQGRLTLSRKF

    • Sequence Length

    • 21

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03487 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03487.

Physicochemical Information

    • Formula

    • C116H187N35O29

    • Absent Amino Acids

    • ACDEHIMNVWY

    • Common Amino Acids

    • FLQR

    • Mass

    • 2535.98

    • PI

    • 12.31

    • Basic Residues

    • 5

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 6

    • Net Charge

    • +5

    • Boman Index

    • -59.78

    • Hydrophobicity

    • -0.886

    • Aliphatic Index

    • 55.71

    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP03487

DRAMP03487 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Functional analysis of four processing products from multiple precursors encoded by a lebocin-related gene from Manduca sexta.

    • Reference

    • Dev Comp Immunol. 2010 Jun;34(6):638-647.

    • Author

    • Rayaprolu S, Wang Y, Kanost MR, Hartson S, Jiang H.