General Information
-
DRAMP ID
- DRAMP03520
-
Peptide Name
- Cecropin-D-like peptide (Insects, animals)
-
Source
- Galleria mellonella (greater wax moth)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- ENFFKEIERAGQRIRDAIISAAPAVETLAQAQKIIKGGD
-
Sequence Length
- 39
-
UniProt Entry
- P85210
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Antifungal
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Target Organism
-
- Gram-positive bacteria: Micrococcus luteus, Listeria monocytogenes, Sarcina Lutea, Escherichia coli D31(MIC=6.9-8.6 µM), Aspergillus niger.
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Free
-
Nonterminal Modifications and Unusual Amino Acids
- Free
-
Stereochemistry
- L
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03520.
Physicochemical Information
-
Formula
- C187H309N55O58
Absent Amino Acids
- CHMWY
Common Amino Acids
- A
Mass
- 4255.84
PI
- 6.43
Basic Residues
- 6
Acidic Residues
- 6
Hydrophobic Residues
- 17
Net Charge
- 0
-
Boman Index
- -75.39
Hydrophobicity
- -0.29
Aliphatic Index
- 95.38
Half Life
-
- Mammalian:1 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 6
DRAMP03520
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Antibacterial peptides of the moth Galleria mellonella.
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Pubmed ID
- 11995991
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Reference
- Acta Biochim Pol. 2001;48(4):1191-1195.
-
Author
- Mak P, Chmiel D, Gacek GJ.
- ·Literature 2
-
Title
- Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.
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Pubmed ID
- 17194500
-
Reference
- Peptides. 2007 Mar;28(3):533-546.
-
Author
- Cytrynska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T.