• DRAMP ID

    • DRAMP03521
    • Peptide Name

    • Proline-rich antimicrobial peptide 1 (Insects, animals)
    • Source

    • Galleria mellonella (Greater wax moth)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • DIQIPGIKKPTHRDIIIPNWNPNVRTQPWQRFGGNKS
    • Sequence Length

    • 37
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Antifungal
    • Target Organism

      • Gram-positive bacterium: Micrococcus luteus(MIC=55.0 µM).
      • Fungi: Pichia pastoris (MIC=16.5 µM), Zygosaccharomyces marxianus (MIC=16.5 µM), Schizosaccharomyces pombe (MIC=11 µM), candida wickerhamii (MIC=16.5 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Free
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03521 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03521.
    • Formula

    • C195H306N60O52
    • Absent Amino Acids

    • ACELMY
    • Common Amino Acids

    • I
    • Mass

    • 4322.95
    • PI

    • 11
    • Basic Residues

    • 7
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 10
    • Net Charge

    • +5
    • Boman Index

    • -91.21
    • Hydrophobicity

    • -1.057
    • Aliphatic Index

    • 71.08
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 11000
    • Absorbance 280nm

    • 305.56
    • Polar Residues

    • 10

DRAMP03521

DRAMP03521 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Antibacterial peptides of the moth Galleria mellonella.
    • Reference

    • Acta Biochim Pol. 2001;48(4):1191-1195.
    • Author

    • Mak P, Chmiel D, Gacek GJ.
  • ·Literature 2
    • Title

    • Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.
    • Reference

    • Peptides. 2007 Mar;28(3):533-546.
    • Author

    • Cytrynska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T.