General Information
-
DRAMP ID
- DRAMP03523
-
Peptide Name
- Anionic antimicrobial peptide 2 (Insects, animals)
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Source
- Galleria mellonella (Greater wax moth)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- ETESTPDYLKNIQQQLEEYTKNFNTQVQNAFDSDKIKSEVNNFIESLGKILNTEKKEAPK
-
Sequence Length
- 60
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UniProt Entry
- P85216
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Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Antifungal
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Target Organism
-
- Gram-positive bacteria: Micrococcus luteus(MIC=43.3-86.6 µM), Listeria monocytogenes (MIC=86.6 µM), Sarcina Lutea (MIC=86.6 µM).
- Fungi: Pichia pastoris (MIC=43.3-86.6 µM), P. stipitis (MIC=43.3-86.6 µM).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Free
-
Nonterminal Modifications and Unusual Amino Acids
- Free
-
Stereochemistry
- L
-
Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP03523.
Physicochemical Information
-
Formula
- C306H484N80O106
Absent Amino Acids
- CHMRW
Common Amino Acids
- EKN
Mass
- 6979.68
PI
- 4.79
Basic Residues
- 8
Acidic Residues
- 11
Hydrophobic Residues
- 15
Net Charge
- -3
-
Boman Index
- -165.01
Hydrophobicity
- -1.183
Aliphatic Index
- 65
Half Life
-
- Mammalian:1 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 2980
Absorbance 280nm
- 50.51
Polar Residues
- 19
DRAMP03523
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Purification and characterization of eight peptides from Galleria mellonella immune hemolymph
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Pubmed ID
- 17194500
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Reference
- Peptides. 2007;28:533-546.
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Author
- Cytrynska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T.