General Information
-
DRAMP ID
- DRAMP03526
-
Peptide Name
- Proline-rich antimicrobial peptide 2 (Insects, animals)
-
Source
- Galleria mellonella (Greater wax moth)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- EIRLPEPFRFPSPTVPKPIDIDPILPHPWSPRQTYPIIARRS
-
Sequence Length
- 42
-
UniProt Entry
- P85212
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+
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Target Organism
-
- Gram-positive bacterium: Micrococcus luteus (MIC=8.6 µM).
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Free
-
Nonterminal Modifications and Unusual Amino Acids
- Free
-
Stereochemistry
- L
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03526.
Physicochemical Information
-
Formula
- C231H358N62O58
Absent Amino Acids
- CGMN
Common Amino Acids
- P
Mass
- 4931.76
PI
- 9.97
Basic Residues
- 7
Acidic Residues
- 4
Hydrophobic Residues
- 13
Net Charge
- +3
-
Boman Index
- -83.39
Hydrophobicity
- -0.583
Aliphatic Index
- 83.57
Half Life
-
- Mammalian:1 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 6990
Absorbance 280nm
- 170.49
Polar Residues
- 6
DRAMP03526
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.
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Pubmed ID
- 17194500
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Reference
- Peptides. 2007 Mar;28(3):533-546.
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Author
- Cytryńska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T.