General Information

    • DRAMP ID

    • DRAMP03539

    • Peptide Name

    • Antifungal protein (Psc-AFP)

    • Source

    • Cullen corylifolium

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • EWEPVQNGGSSYYMVPRIWA

    • Sequence Length

    • 20

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Alternaria brassicae (MIC=10 µM), Aspergillus niger (MIC=10 µM), Fusarium oxysporum (MIC=10 µM), Rhizoctonia cerealis (MIC=10 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • Free

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03539 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03539.

Physicochemical Information

    • Formula

    • C109H153N27O31S

    • Absent Amino Acids

    • CDFHKLT

    • Common Amino Acids

    • EGPSVWY

    • Mass

    • 2369.64

    • PI

    • 4.53

    • Basic Residues

    • 1

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 6

    • Net Charge

    • -1

    • Boman Index

    • -24.1

    • Hydrophobicity

    • -0.595

    • Aliphatic Index

    • 53.5

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 13980

    • Absorbance 280nm

    • 735.79

    • Polar Residues

    • 7

DRAMP03539

DRAMP03539 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Psc-AFP, an antifungal protein with trypsin inhibitor activity from Psoralea corylifolia seeds

    • Reference

    • Peptides. 27:1726-1731(2006)

    • Author

    • Yang X, Li J, Wang X, Fang W, Bidochka M.J, She R, Xiao Y, Pei Y.