General Information

    • DRAMP ID

    • DRAMP03545

    • Peptide Name

    • LLP Lentivirus lytic peptide (Human, mammals, animals)

    • Source

    • Homo sapiens (Human)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RVIEVVQGACRAIRHIPRRIRQGLERIL

    • Sequence Length

    • 28

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Not found

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03545 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03545.

Physicochemical Information

    • Formula

    • C143H255N53O35S

    • Absent Amino Acids

    • DFKMNSTWY

    • Common Amino Acids

    • R

    • Mass

    • 3308.99

    • PI

    • 11.88

    • Basic Residues

    • 8

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +6

    • Boman Index

    • -80.46

    • Hydrophobicity

    • -0.082

    • Aliphatic Index

    • 135.71

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP03545

DRAMP03545 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Novel antimicrobial peptides derived from human immunodeficiency virus type 1 and other lentivirus transmembrane proteins.

    • Reference

    • Antimicrob Agents Chemother. 1997 Nov;41(11):2394-2398.

    • Author

    • Tencza SB, Douglass JP, Creighton DJ Jr, Montelaro RC, Mietzner TA.