General Information

    • DRAMP ID

    • DRAMP03546

    • Peptide Name

    • SgII peptide A (Human, mammals, animals)

    • Source

    • Homo sapiens (Human)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • KQEGRDHDKSKGHFHMIVIHHKGGQAHHG

    • Sequence Length

    • 29

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Not found

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03546 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03546.

Physicochemical Information

    • Formula

    • C142H218N52O39S

    • Absent Amino Acids

    • CLNPTWY

    • Common Amino Acids

    • H

    • Mass

    • 3309.68

    • PI

    • 9.53

    • Basic Residues

    • 12

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +9

    • Boman Index

    • -82.75

    • Hydrophobicity

    • -1.486

    • Aliphatic Index

    • 40.34

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 6

DRAMP03546

DRAMP03546 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins.

    • Reference

    • J Immunol. 2008 Sep 1;181(5):3413-3421.

    • Author

    • Edström AM, Malm J, Frohm B, Martellini JA, Giwercman A, Mörgelin M, Cole AM, Sørensen OE.