• DRAMP ID

    • DRAMP03578
    • Peptide Name

    • Histatin-3 (His-rich; Human, mammals, animals)
    • Source

    • Homo sapiens (Human)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN
    • Sequence Length

    • 32
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal
    • Target Organism

      • Yeast: Candida albicans (98.5±0.5 % inhibition at 54 nmol)
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Rich
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03578 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03578.
    • Formula

    • C178H258N64O48
    • Absent Amino Acids

    • CIMPQTVW
    • Common Amino Acids

    • H
    • Mass

    • 4062.41
    • PI

    • 9.99
    • Basic Residues

    • 15
    • Acidic Residues

    • 3
    • Hydrophobic Residues

    • 3
    • Net Charge

    • +12
    • Boman Index

    • -151.2
    • Hydrophobicity

    • -2.297
    • Aliphatic Index

    • 15.31
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5960
    • Absorbance 280nm

    • 192.26
    • Polar Residues

    • 11

DRAMP03578

DRAMP03578 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans.
    • Reference

    • J Biol Chem. 1988 Jun 5;263(16):7472-7477
    • Author

    • Oppenheim FG, Xu T, McMillian FM, Levitz SM, Diamond RD, Offner GD, Troxler RF1988