General Information

    • DRAMP ID

    • DRAMP03581

    • Peptide Name

    • Histatin 6 (His-rich; Human, mammals, animals)

    • Source

    • Homo sapiens (Human)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • DSHAKRHHGYKRKFHEKHHSHRGYR

    • Sequence Length

    • 25

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Rich

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03581 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03581.

Physicochemical Information

    • Formula

    • C139H207N55O34

    • Absent Amino Acids

    • CILMNPQTVW

    • Common Amino Acids

    • H

    • Mass

    • 3192.52

    • PI

    • 10.62

    • Basic Residues

    • 15

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 2

    • Net Charge

    • +13

    • Boman Index

    • -130.44

    • Hydrophobicity

    • -2.536

    • Aliphatic Index

    • 4

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 124.17

    • Polar Residues

    • 6

DRAMP03581

DRAMP03581 chydropathy plot

Comments Information

    • An autoproteolytic product from Histatin 3.

Literature Information

  • ·Literature 1

    • Title

    • Structural relation between human salivary histatins.

    • Reference

    • J Dent Res 1990; 69: 2-6.

    • Author

    • Troxler RF et al Oppenheim FG.