General Information

    • DRAMP ID

    • DRAMP03584

    • Peptide Name

    • Histatin 9 (His-rich; Also detected are Histatin 10; Human, mammals, animals)

    • Source

    • Homo sapiens (Human)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RKFHEKHHSHRGYR

    • Sequence Length

    • 14

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Rich

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03584 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03584.

Physicochemical Information

    • Formula

    • C82H123N33O19

    • Absent Amino Acids

    • ACDILMNPQTVW

    • Common Amino Acids

    • H

    • Mass

    • 1875.09

    • PI

    • 11

    • Basic Residues

    • 9

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 1

    • Net Charge

    • +8

    • Boman Index

    • -80.93

    • Hydrophobicity

    • -2.664

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 114.62

    • Polar Residues

    • 3

DRAMP03584

Comments Information

    • An autoproteolytic product from Histatin 3 (residues 12-25). Histatin 12=residues 5-10; histatin 11=residues 5-11; Histatin 10=residues 13-25. Antimicrobial activities of Histatins 10-12 are Comment

    • No comments found on DRAMP databasen.

Literature Information

  • ·Literature 1

    • Title

    • Histatins 2 and 4 are autoproteolytic degradation products of human parotid saliva.

    • Reference

    • Oral Microbiol Immunol 1992; 7: 127-128.

    • Author

    • Xu L, Lal K, Pollock JJ.