General Information

    • DRAMP ID

    • DRAMP03665

    • Peptide Name

    • Lysozyme

    • Source

    • Lysobacter sp. (strain XL1)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • IAIQGGXGYLXQPGDGYKYA

    • Sequence Length

    • 20

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03665 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03665.

Physicochemical Information

    • Formula

    • C86H123N21O24

    • Absent Amino Acids

    • CEFHMNRSTVW

    • Common Amino Acids

    • G

    • Mass

    • 2093.74

    • PI

    • 5.83

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 5

    • Net Charge

    • 0

    • Boman Index

    • -2.69

    • Hydrophobicity

    • -0.275

    • Aliphatic Index

    • 68.5

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 4470

    • Absorbance 280nm

    • 235.26

    • Polar Residues

    • 8

DRAMP03665

DRAMP03665 chydropathy plot

Comments Information

    • Biophysicochemical properties

    • Optimum pH is 8.0; Optimum temperature is 60 degrees Celsius.

    • Also has Catalytic activity

    • Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Literature Information

  • ·Literature 1

    • Title

    • Identification of extracellular bacteriolytic enzymes from Lysobacter sp. XL1.

    • Reference

    • Submitted (APR-2007) to UniProtKB.

    • Author

    • Muranova T.A, Stepnaya O.A, Tsfasman I.M, Kulaev I.S.