General Information
-
DRAMP ID
- DRAMP03669
-
Peptide Name
- Megourin-2 (arthropod; animals)
-
Source
- Megoura viciae (Vetch aphid)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- YLDVNQIASYLLCLGQGAVFNGRKTCQIGCRAACQQPGCGGYKECEQIPNIRLHKYRCHCNSG
-
Sequence Length
- 63
-
UniProt Entry
- P83418
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal
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Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03669.
Physicochemical Information
-
Formula
- C295H468N92O87S8
Absent Amino Acids
- MW
Common Amino Acids
- CG
Mass
- 6952
PI
- 8.71
Basic Residues
- 9
Acidic Residues
- 3
Hydrophobic Residues
- 16
Net Charge
- +6
-
Boman Index
- -97.38
Hydrophobicity
- -0.319
Aliphatic Index
- 71.27
Half Life
-
- Mammalian:2.8 hour
- Yeast:10 min
- E.coli:2 min
Extinction Coefficient Cystines
- 6460
Absorbance 280nm
- 104.19
Polar Residues
- 27
DRAMP03669
Comments Information
Function
- Has antimicrobial activity against Gram-positive bacteria and fungi.
Induction
- By bacterial infection.
PTM
- Contains four disulfide bonds.
Literature Information
- ·Literature 1
-
Title
- Unknown
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Pubmed ID
- PubMed ID is not available
-
Reference
- Submitted (JUL-2002) to UniProtKB
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Author
- Bulet P, Charlet M, Chernish S, Hetru C.