• • DRAMP ID

  • DRAMP03679

• • Peptide Name

  • Cathelicidin-2 (Bactenecin-5, Bac5; ChBac5; ruminant, animals)

• • Source

  • Capra hircus (Goat)

• • Family

  • Not found

• • Gene

  • CATHL2

• • Sequence

  • RFRPPIRRPPIRPPFNPPFRPPVRPPFRPPFRPPFRPPIGPFP

• • Sequence Length

  • 43

• • UniProt Entry

  • P82018,Q4JFB9

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacteria: Escherichia coli (MIC=1 µg/ml), Salmonella typhimurium (MIC=1 µg/ml), Pseudomonas aeruginosa (MIC=1 µg/ml);
    • Gram-positive bacteria: Staphylococcus aureus (MIC<2 µg/ml), Listeria monocytogenes (MIC<2 µg/ml) and Bacillus subtilis (MIC<2 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Lipopolysaccharide (LPS)-binding

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP03679.

DRAMP03679

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Purification and properties of proline-rich antimicrobial peptides from sheep and goat leukocytes.

• • Pubmed ID

  • 10417180

• • Reference

  • nfect Immun. 1999 Aug;67(8):4106-4111.

• • Author

  • Shamova O, Brogden KA, Zhao C, Nguyen T, Kokryakov VN, Lehrer RI.