• DRAMP ID

    • DRAMP03713
    • Peptide Name

    • Peptide Hp1035 (Non-disulfide-bridged peptide 5.10, NDBP-5.10; Arthropods, animals)
    • Source

    • Heterometrus petersii (Asian forest scorpion)
    • Family

    • Belongs to the scorpion NDBP 5 family
    • Gene

    • Not found
    • Sequence

    • IFSAIGGFLKSIF
    • Sequence Length

    • 13
    • Protein Existence

    • Transcript level
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP03713 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP03713.
    • Formula

    • C70H106N14O16
    • Absent Amino Acids

    • CDEHMNPQRTVWY
    • Common Amino Acids

    • FI
    • Mass

    • 1399.7
    • PI

    • 8.75
    • Basic Residues

    • 1
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 8
    • Net Charge

    • +1
    • Boman Index

    • 19.96
    • Hydrophobicity

    • 1.631
    • Aliphatic Index

    • 127.69
    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 4

DRAMP03713

    • Function

    • Amphipathic peptide with probable antibacterial activities. Hp1035 peptide, showing high homology to Hp1090, exhibited no anti-HCV activity.
    • Tissue specificity

    • Expressed by the venom gland.
    • PTM

    • C-terminal amidation (By similarity).
  • ·Literature 1
    • Title

    • A new natural alpha-helical peptide from the venom of the scorpion Heterometrus petersii kills HCV.
    • Reference

    • Peptides. 2011 Jan;32(1):11-19.
    • Author

    • Yan R, Zhao Z, He Y, Wu L, Cai D, Hong W, Wu Y, Cao Z, Zheng C, Li W.