General Information

    • DRAMP ID

    • DRAMP03725

    • Peptide Name

    • Non-disulfide-bridged peptide 5.5 (NDBP-5.5; Arthropods, animals)

    • Source

    • Hadrurus gertschi (Scorpion)

    • Family

    • Belongs to the scorpion NDBP 5 family

    • Gene

    • Not found

    • Sequence

    • IFSAIAGLLSNLL

    • Sequence Length

    • 13

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • [Ref.17506894]Weak hemolytic activity against sheep red blood cells

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Alpha helix

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03725 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03725.

Physicochemical Information

    • Formula

    • C63H106N14O17

    • Absent Amino Acids

    • CDEHKMPQRTVWY

    • Common Amino Acids

    • L

    • Mass

    • 1331.62

    • PI

    • 5.52

    • Basic Residues

    • 0

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 9

    • Net Charge

    • 0

    • Boman Index

    • 23.62

    • Hydrophobicity

    • 1.931

    • Aliphatic Index

    • 195.38

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP03725

Comments Information

    • Function

    • Has weak hemolytic activity.

Literature Information

  • ·Literature 1

    • Title

    • Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones).

    • Reference

    • BMC Genomics. 2007 May 16;8:119.

    • Author

    • Schwartz E.F, Diego-Garcia E, Rodriguez de la Vega R.C, Possani L.D.