General Information

    • DRAMP ID

    • DRAMP03726

    • Peptide Name

    • Non-disulfide-bridged peptide 5.6 (NDBP-5.6; Arthropods, animals)

    • Source

    • Hadrurus gertschi (Scorpion)

    • Family

    • Belongs to the scorpion NDBP 5 family

    • Gene

    • Not found

    • Sequence

    • FIFDLLKKLV

    • Sequence Length

    • 10

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • [Ref.17506894]Weak hemolytic activity against sheep red blood cells

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Alpha helix

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03726 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03726.

Physicochemical Information

    • Formula

    • C63H102N12O13

    • Absent Amino Acids

    • ACEGHMNPQRSTWY

    • Common Amino Acids

    • L

    • Mass

    • 1235.58

    • PI

    • 8.59

    • Basic Residues

    • 2

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +1

    • Boman Index

    • 9.86

    • Hydrophobicity

    • 1.44

    • Aliphatic Index

    • 185

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 0

DRAMP03726

Comments Information

    • Function

    • Has weak hemolytic activity.

Literature Information

  • ·Literature 1

    • Title

    • Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones).

    • Reference

    • BMC Genomics. 2007 May 16;8:119.

    • Author

    • Schwartz E.F, Diego-Garcia E, Rodriguez de la Vega R.C, Possani L.D.